Mild Memory Loss With Aging as a Disease

The process of declaring parts of aging as a disease is driven by regulation: the FDA does not permit treatments for aging, only for named diseases. Since there is little funding for research that cannot be legally commercialized, the incentive is to carve off chunks of the process of aging and go through the process of having government employees add it to the list of diseases - which can take years and millions of dollars. Sarcopenia, for example, is still not recognized by the FDA, meaning that no potential treatment can be commercially developed in the US. Here is an example of this process at work for memory loss: "Simply getting older is not the cause of mild memory lapses often called senior moments, according to a new study ... even the very early mild changes in memory that are much more common in old age than dementia are caused by the same brain lesions associated with Alzheimer's disease and other dementias. ... The very early mild cognitive changes once thought to be normal aging are really the first signs of progressive dementia, in particular Alzheimer's disease. The pathology in the brain related to Alzheimer's and other dementias has a much greater impact on memory function in old age than we previously recognized. ... dementias are the root cause of virtually all loss of cognition and memory in old age. They aren't the only contributing factors; other factors affect how vulnerable we are to the pathology and to its effects. But the pathology does appear to be the main force that is driving cognitive decline in old age."

Link: http://www.rush.edu/webapps/MEDREL/servlet/NewsRelease?ID=1420

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