Methuselah Yeast, Worms
An article from last month in PLoS Biology reviews work by David Sinclair on the biology and genetics of aging in yeast and Cynthia Kenyon on aging in nematode worms. Both have managed significant (one might say radical) healthy life extension in their test subjects, although science is still far from taking this knowledge and using it to extend the healthy human life span. The more we know, the closer we get, however: every step forward is a step taken towards longer, healthier lives for you and I. If you're scientifically minded, don't forget to scroll down past the references to read the interesting end comments as well.
Link: http://www.plosbiology.org/plosonline/?request=get-document&doi=10.1371%2Fjournal.pbio.0020012