How Does Regeneration Work?

Transfusions of adult stem cells have shown promise in human trials, but researchers are still searching for definitive conclusions on how these therapies work. From EurekAlert: "Adult stem cells can be found locally in various tissues and organs, and we have presumed that they are participating in the repair and maintenance of organ functions. The controversial idea is that adult stem cells have the potential for transdifferentiation; in other words, that they are able to transmutate from one type of organ cell to another. ... [Scientists] have discovered by a number of different experimental approaches that mesenchymal stem cells only show a rudimentarily developed potential for transdifferentiation processes. All cases in which functional skeletal muscle cells arose from mesenchymal stem cells were based on the fusion of stem cells with already differentiated muscle cells."

Link: http://www.eurekalert.org/pub_releases/2005-08/m-tro080405.php

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